The Aidan O’Brien-trained River Tiber is a late withdrawal from Friday night’s Breeders’ Cup Juvenile Turf.
Jessica Harrington's Givemethebeatboys is also a late absentee from the Grade 1.
Victorious in the Group 2 Norfolk Stakes at Royal Ascot, River Tiber would have been trying the mile for the first time after two placings behind Vandeek in Group 1 company.
O'Brien remains double-handed in the Breeders' Cup Juvenile Turf with Prix Jean-Luc Lagardere second Unquestionable and Dundalk Listed winner Mountain Bear.
Ryan Moore is expected to switch to Unquestionable, who finished second in the Group 2 Railway Stakes before his excellent runner-up finish behind Rosallion in the Prix Jean-Luc Lagardere.
"Ryan was delighted with him in France and said the split just came a little bit too early for him and he had to go early," said O'Brien.
"Obviously when the split came he had to go and he would have just preferred to wait a little bit longer. He ran a very good race.
"We always felt a mile would be well within his compass and he's in very good form and has a nice draw as well."