John Quinn's superstar mare heads a sixteen-strong field as she bids to join the likes of Battaash and land back-to-back Nunthorpe Stakes.
Last year's heroine returned to winning ways in the King George Stakes at Glorious Goodwood last time but will have to face her Royal Ascot conquerors Bradsell and Khaadem once more.
The Archie Watson-trained Bradsell hasn't been seen since his sparkling success in the King's Stand Stakes, while Khaadem, who caused such a shock when taking out the six-furlong Queen Elizabeth II Jubilee Stakes, will be hoping to bounce back from his July Cup disappointment.
Aidan O'Brien will be expecting a big week and he relies on Aesop's Fables in the five-furlong dash. Ryan Moore will take the ride, while Frankie Dettori partners King's Stand Stakes' fourth Twilight Calls for the first time.
No two-year-old has landed the Nunthorpe since Kingsgate Native landed the contest 16 years ago. The gutsy Group 3 Molecomb Stakes winner will be partnered by Hong Kong-bound jockey Andrea Atzeni, with regular rider Jason Hart understandably continuing his partnership on Highfield Princess.
Karl Burke's filly Dramatised produced a taking performance in the Temple Stakes at Haydock on her reappearance, and owners Clipper Logistics will be expecting a better run than when down the field at Royal Ascot.
Ed Bethell's Regional takes the step up to top-level company following his impressive victory in the Listed Sky Bet Achilles Stakes at Haydock in June.
Sean Kirrane will have his first taste of Group 1 racing onboard Adam West's Live In The Dream, while Equality looks to regain the winning thread for Charlie Hills and Dan Muscutt.
Ladies Church, Makarova, Nymphadora, Get Ahead, Queen Me and Tees Spirit complete the field of sixteen for Friday's feature.
