The seven-race card at Haydock Park on July 7 also opens with the £100,000 bet365 Handicap (12.35pm, 17 entries), staged over a mile and a half for three-year-olds.
Also featuring on the card is the £93,000 bet365 Lancashire Oaks (1.10pm, 14 entries) over a mile and a half for fillies and mares.
The possible field includes the progressive four-year-old Precious Ramotswe (John Gosden, 11/2 with bet365), who is unbeaten in her two starts so far this year, most recently taking a G3 contest at York. Along with the late Sir Henry Cecil, Gosden is the most successful trainer in the Lancashire Oaks with seven wins, most recently The Black Princess in 2017.
Horseplay (Andrew Balding, 3/1 favourite) was fourth to Enable in the 2017 Investec Oaks at Epsom Downs and came home second to Coronet in the G2 Middleton Stakes at York in May.
Luca Cumani, twice successful in the Lancashire Oaks, has entered God Given (4/1), successful last time out over the course and distance in the G3 Betway Pinnacle Stakes on June 9.
There is Irish interest, with Aidan O'Brien entering recent G3 Munster Oaks heroine Flattering (9/2) and Jim Bolger putting in the Listed-placed Cimeara (12/1). There is also a possible raider from France in Gaining (Henri Francois Devin, 8/1), owned by Khalid Abdullah, and a close fourth last time out in the G3 Prix Corrida at Saint-Cloud in May.
bet365 Lancashire Oaks, bet365 bet:
3/1 Horseplay
4/1 God Given
9/2 Flattering
11/2 Precious Ramotswe
13/2 Isabel de Urbina
8/1 Star Rock, Gaining
10/1 What A Home, Mrs Sippy
12/1 Cimeara
14/1 Euro Nightmare
16/1 Dramatic Queen
20/1 Lady of Shalott
25/1 Snowy Winter
EW 1/5 - 1, 2, 3